It got harder and harder to stay awake, By day three I started hallucinating. Lasted about 3-4 weeks. You probably will lose some mental and physiological defense systems. I remember one time I had to take steroids for a week. I don't know what to do. Lots of coffee, loud music, brisk walks, and utter desperation. Been there myself many times... As for the 'dire consequences' of a lack of sleep, as a medical layman I say to you: don't worry about it excessively. I havent slept in 4-5 days, and by that I don't mean poor sleep, I mean I have NOT slept at all for 4 days. Science says this is actually a good thing to do occasionally. Don’t binge eat after. sleep effects the chemistry of the body so a dramatic shift in sleep pattern will produce the effect you describe. If you have been able to sleep well before, the first thing to do is to figure out what may recently have changed. And those changes should help you survive the day. Does your doctor have you on any type of steroid medication? I haven't slept in about 48 hours. Also you will be hungry. I've tried laying down and going to sleep, but its like trying to go to bed when you're totally wide awake. Although you should avoid going longer than 3-4 days without sleep, you can safely stay up for a few days as long as you plan to get full nights of sleep for 1-2 days afterwards. I slept but only about 15-20 minutes a day of real sleep. For the first 17-18 hours, you don't really feel much except a little routine tiredness. I'm tired, but I just cannot get to sleep. I've layed in bed for hours. No big deal. So I actually have recent experience with this. I feel your pain..! This may give you a clue as to the reason for your insomnia: * New supplements, medications, foods, beverages? I like the answers you received and just have one question. Some people said I looked like death others just did a double take stare like they saw a zombie. Scott Kelley, a 10-year Army veteran, knows about sleep deprivation. With multiple deployments under his belt, Kelley has had many instances of … My body is ready for bed, but my brain is not. I once stayed up for four days in grad school to finish some projects. At this point the muscle fatigue is really bad to the point that even sitting up is just... heavy. … after a few years you graduate with a degree in medicine. After the first night, I couldn’t sleep. Is this still a problem ?! I have been taking Melatonin or Lorazepam and neither seems to work for me. X Research source With a little bit of preparation and a regular schedule, you'll be able to stay awake and push through to the end. TLDR: Not a whole heck of a lot that you can tell. Seriously, though, welcome to the world of quite a few professions during their university years. Exercise will also help you sleep better at night. 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