Isophorone Diisocyanate. Reaction with water to form Carbon Dioxide [Merck 11th ed. Catalog Number Cat. Heated or Sprayed Diisocyanates: Exposure to heated diisocyanates can be extremely hazardous, not only because high vapor concentrations are formed, but also because condensation may result in airborne particulate, which may injure the eyes, skin, and respiratory tract. 0000052031 00000 n TOLUENE-2,6-DIISOCYANATE reacts violently with amines, alcohols, bases and warm water, causing fire and explosion hazards. 1989]. Reported as not meeting GHS hazard criteria by 1 of 1196 companies. ���Y? Reaction with water liberates carbon dioxide. Signs and Symptoms of Acute Toluene 2,6-Diisocyanate Exposure: Signs and symptoms of acute exposure to toluene 2,6-diisocyanate may be severe and include burning of the skin, eyes, nose, and throat. Autres études. 0000006881 00000 n 8. Le contact direct avec la peau peut entraîner des dermatites graves ou de l’eczéma. Login to download SDS . (February 1996). Exposure, hazard and risk 1 ... Methylenediphenyl diisocyanate (MDI) and toluene diisocyanate (TDI) are the most important commercial products in the family of organic chemicals having two or more isocyanate groups in the molecule. 0000007141 00000 n <]>> Toluene is typically used in a mixture with other solvents and chemicals such as paint pigments. (April 1996). State California Office of Environmental Health Hazards Toluene Diisocyanates (2,4 and 2,6) 2016 Overview of Reference Exposure Levels (RELs) Although not statistically significant, rare brain tumors were found in rats exposed to TDI (two … Toluene-2,6-Diisocyanate. 4�?c~��D�x Linear Formula CH 3 C 6 H 3 (NCO) 2. 0000001407 00000 n Regulatory information United States of America Inventory Component CAS-No TSCA TSCA Inventory notification - Active/Inactive TSCA - EPA Regulatory Flags Toluene 2,4-diisocyanate 584-84-9 X ACTIVE SP Toluene 2,6-diisocyanate 91-08-7 X ACTIVE SP Legend: TSCA - Toxic Substances Control Act, (40 CFR Part … Toluene (/ ˈ t ɒ lj u iː n /), also known as toluol (/ ˈ t ɒ lj u ɒ l /), is an aromatic hydrocarbon.It is a colorless, water-insoluble liquid with the smell associated with paint thinners.It is a mono-substituted benzene derivative, consisting of a methyl group (CH₃) attached to a phenyl group.As such, its IUPAC systematic name is methylbenzene. Potentially violent polymerization reaction with strong bases or acyl chlorides. Ship Type. Compendium of Chemical Hazards: Toluene diisocyanate Page 3 of 4 General Information Ingestion of toluene diisocyanate may cause nausea, vomiting and abdominal pain. 1 0 obj The Office of Environmental Health Hazard Assessment (OEHHA) is required to develop guidelines for conducting health risk assessments under … Reaction with water to form Carbon Dioxide [Merck 11th ed. endobj Signal: Danger GHS Hazard Statements Aggregated GHS information provided by 1196 companies from 27 notifications to the ECHA C&L Inventory. Toluene is typically used in a mixture with other solvents and chemicals such as paint pigments. endobj * Many scientists believe there is no safe level of exposure to a carcinogen. ), Category 1 H330 Fatal if inhaled Skin corrosion/irritation, Category 2 H315 Causes skin irritation Serious eye damage/eye irritation, Category 2A H319 Causes serious eye irritation 0000004058 00000 n Warning: Toluene 2,6-diisocyanate is a powerful irritant to the lungs, skin, eyes, and gastrointestinal tract. Melting point. * Many scientists believe there is no safe level of exposure to a carcinogen. Boiling points. Tank Type. INTRODUCTION 14 III. 0000001270 00000 n 2 0 obj Toluene Diisocyanate (TDI) and Toluenediamine: Evidence of Carcinogenicity: 2014 Chemical and physical properties, exposure limits, studies of carcinogenicity. Toluene is a clear, colorless liquid which becomes a vapor when exposed to air at room temperature. 0000066022 00000 n Toluene diisocyanate (TDI) is an organic compound with the formula CH 3 C 6 H 3 (NCO) 2.Two of the six possible isomers are commercially important: 2,4-TDI (CAS: 584-84-9) and 2,6-TDI (CAS: 91-08-7). SAFETY DATA SHEET Revision Date 21-Feb-2020 Revision Number 2 1. Toluene vapor has a sharp or sweet odor, which is a sign of exposure. %���� The polyurethanes have found wide applications as solid elastomers, flexible foaming materials etc. Les isocyanates, notamment le toluène de diisocyanate (TDI), et l'hexaméthylène di-isocyanate (HDI) constituent la première cause d’asthme chimique professionnel. 2,4-TDI is produced in the pure state, but TDI is often marketed as 80/20 and 65/35 mixtures of the 2,4 and 2,6 isomers respectively. 4 0 obj 1989]. Relevant additional IBC req. 0 Storage Condition Storage. Caution is advised. 0000004823 00000 n (April 1996). 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